We are noticing that the world is undergoing rapid transformation, and the geopolitical situation is changing very dynamically. The change in the balance of power in connection with the war in Ukraine, the internal tensions and transformations within the European Union, the attempt of the EU institutions to exert pressure on the EU Member States from Central and Eastern Europe in the shaping of their internal policies - all this makes cooperation within the framework of the Inter-Mediterranean Region a civilizational necessity in the near and distant future.